Allergy & Immunology
Allergy and Immunology is a rapidly advancing field focused on understanding and treating immune system disorders such as allergic, autoimmune and autoinflammatory diseases and immunodeficiencies. Dr. Vince Clinical Research (DVCR) has experience across a broad range of allergic and immunologic disorders, from common food allergies to atopic dermatitis. Our investigator team has participated in dozens of complex allergy and immunology trials across all phases of research. One of DVCR’s Principal Investigators, William J. Lavery, MD, PhD, is certified by the American Board of Allergy and Immunology and oversees the conduct of these trials.
Capabilities
As a full-service CRO, Dr. Vince Clinical Research provides end-to-end clinical trial solutions from protocol writing through CSR publishing. We conduct the following studies in both healthy volunteers and patient populations at our physician-led Phase 1 clinical pharmacology unit and at our global network of strategic site partners:
- First-in-Human (FIH):
- KSingle Ascending Dose (SAD) which may include:
- [Early QT/cardiac safety in partnership with Clario
- [Food Effect cohort
- KMultiple Ascending Dose (MAD) which may include:
- [Patient cohorts
- KCombined SAD/MAD which may include:
- [Patient cohorts
- NDA-enabling clinical pharmacology studies:
- KDrug-Drug Interaction
- KThorough QT/QTc in partnership with Clario
- KFood Effect
- KBioavailability/Bioequivalence
- KPharmacokinetic/Pharmacodynamic
- Vaccine studies
- Phase Ib/IIa Proof-of-Concept (POC)
- Phase II multi-site patient trials
Many of these trial types involve procedures, assessments and questionnaires which are specific to allergy and immunology clinical trials such as:
- Spirometry
- Pulmonary Function Testing (PFT)
- Skin and Serum Allergy Testing
- Atopic Dermatitis Assessments
Click below to receive more information on how our CRO can support your upcoming allergy and immunology trial.
Indications
DVCR’s medical, scientific, clinical operations and project management teams have participated in allergy and immunology clinical trials across multiple related indications. Additionally, for multi-site trials, DVCR has built a global network of strategic partner sites with vast experience enrolling patient populations.
Allergies and Hypersensitivity
- Allergic Rhinitis/Conjunctivitis (Hay Fever)
- Atopic Dermatitis
- Eosinophilic Esophagitis
- Food Allergies
- Urticaria/Angioedema (Hives)
- Allergic Asthma
Immunologic Disorders
- Irritable Bowel Syndrome (Crohn’s Disease and Ulcerative Colitis)
- Autoimmune Disorders
- Psoriasis
- Immunodeficiency Disorders
- Autoinflammatory Disorders
Meet Our Experts
To ensure the successful execution of your clinical trial, DVCR is dedicated to providing a team of clinical staff with extensive experience in allergy and immunology studies. The following members of our company are heavily involved in the oversight, planning, and day-to-day conduct of your clinical studies:
William J. Lavery, MD, PhD
Principal Investigator
Bio
Dr. William Lavery serves as a Principal Investigator at DVCR. He has participated in over 50 clinical trials as a Principal Investigator or Sub-Investigator and is board-certified by the American Board of Allergy and Immunology. In his journey to become a Physician Scientist, Dr. Lavery earned a PhD in Molecular and Cellular Physiology. Dr. Lavery has published over a dozen peer-reviewed research articles and book chapters as well as presented at numerous national meetings. Prior to joining DVCR, he worked in private practice treating adult and pediatric patients for various allergy, asthma and immunologic disorders.
Michelle Neaderhiser
Director, Study Management
Bio
Michelle Neaderhiser is a registered nurse with over 25 years of clinical research experience. Her expertise is in the management of Clinical Operations and Study Management for Phase 1 clinical trials. She focuses on completing comprehensive protocol reviews as they relate to operationalizing trials for clinical conduct. She is known for collaboratively working with multiple departments to effectively conduct trials from study start-up through final report. She prides herself on prioritizing client requests and providing excellent customer service.
Lora Adriano
Senior Study Manager
Meet Our Experts
To ensure the successful execution of your clinical trial, DVCR is dedicated to providing a team of clinical staff with extensive experience in allergy and immunology studies. The following members of our company are heavily involved in the oversight, planning, and day-to-day conduct of your clinical studies:
William J. Lavery, MD, PhD
Principal Investigator
Bio
Dr. William Lavery serves as a Principal Investigator at DVCR. He has participated in over 50 clinical trials as a Principal Investigator or Sub-Investigator and is board-certified by the American Board of Allergy and Immunology. In his journey to become a Physician Scientist, Dr. Lavery earned a PhD in Molecular and Cellular Physiology. Dr. Lavery has published over a dozen peer-reviewed research articles and book chapters as well as presented at numerous national meetings. Prior to joining DVCR, he worked in private practice treating adult and pediatric patients for various allergy, asthma and immunologic disorders.
Michelle Neaderhiser
Director, Study Management
Bio
Michelle Neaderhiser is a registered nurse with over 25 years of clinical research experience. Her expertise is in the management of Clinical Operations and Study Management for Phase 1 clinical trials. She focuses on completing comprehensive protocol reviews as they relate to operationalizing trials for clinical conduct. She is known for collaboratively working with multiple departments to effectively conduct trials from study start-up through final report. She prides herself on prioritizing client requests and providing excellent customer service.
Lora Adriano
Senior Study Manager
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Meet Our Experts
To ensure the successful execution of your clinical trial, DVCR is dedicated to providing a team of clinical staff with extensive experience in allergy and immunology studies. The following members of our company are heavily involved in the oversight, planning, and day-to-day conduct of your clinical studies:
William J. Lavery, MD, PhD
Principal Investigator
Bio
Dr. William Lavery serves as a Principal Investigator at DVCR. He has participated in over 50 clinical trials as a Principal Investigator or Sub-Investigator and is board-certified by the American Board of Allergy and Immunology. In his journey to become a Physician Scientist, Dr. Lavery earned a PhD in Molecular and Cellular Physiology. Dr. Lavery has published over a dozen peer-reviewed research articles and book chapters as well as presented at numerous national meetings. Prior to joining DVCR, he worked in private practice treating adult and pediatric patients for various allergy, asthma and immunologic disorders.
Michelle Neaderhiser
Director, Study Management
Bio
Michelle Neaderhiser is a registered nurse with over 25 years of clinical research experience. Her expertise is in the management of Clinical Operations and Study Management for Phase 1 clinical trials. She focuses on completing comprehensive protocol reviews as they relate to operationalizing trials for clinical conduct. She is known for collaboratively working with multiple departments to effectively conduct trials from study start-up through final report. She prides herself on prioritizing client requests and providing excellent customer service.
Lora Adriano
Senior Study Manager
